articles and reviews

Scientific publications

A bibliographic stream of laboratory papers, reviews, journal records, and attached materials.

Design and anti-rhinovirus activity of novel derivatives based on the pleconaril core

A. Egorova,O. Riabova,E. Kazakova,S. de Jonghe,D. Jochmans,J. Neyts,M. Schmidtke,M. Cogoni,V. Palmas,M. Khrenova,G. Sanna,V. Makarov

European Journal of Medicinal Chemistry. 2026-08-28

Open record

2026-08-19

Studies in Natural Products Chemistry

Полусинтетический алкалоид виндебурнол: синтез и его влияние на центральную нервную систему

L. Borets,Y. Zorkina,O. Abramova,V. Ushakova,E. Zubkov,V. Makarov

Studies in Natural Products Chemistry. 2026-08-19

Open record

2026-08-15

Journal of Electroanalytical Chemistry

Photoelectrocatalytic oxidation of levofloxacin on titanium dioxide nanotubes in a 0.9% NaCl solution

V. Grinberg,V. Emets,V. Makarov,O. Riabova,A. Averin,N. Mayorova

Journal of Electroanalytical Chemistry. 2026-08-15

Open record

2026-07-22

Neuroscience and Biobehavioral Reviews

Ultrasound model of depression in rodents: a comprehensive analysis of validity, pathogenic mechanisms, and potential for translation to humans

A. Avdaseva,V. Ushakova,O. Abramova,Y. Zorkina,E. Zubkov,V. Makarov,V. Chekhonin,A. Morozova

Neuroscience and Biobehavioral Reviews. 2026-07-22

Open record

2026-06-09

Microbiology and Molecular Biology Reviews

Effective Influenza Treatment: A Comprehensive Review of Challenges and Advances

K. Pomeshikova,A. Poromov,M. Schmidtke,V. Makarov

Microbiology and Molecular Biology Reviews. 2026-06-09

Open record

2026-05-25

ACS Infection Diseases

The efficacy, structure-activity relationship, and mode of action studies of a new generation of acridine/acridone-based antimalarials

S. Maluf,G. Mendes,I. Moura,G. de Souza,T. Valdes,V. Bonatto,G. Oliveir,A. Oliveir,M. Gazarini,A. Puhl,N. Monakhova,A. Lepioshkin,V. Makarov,T. Lane,R. Raman,G. Campolina,C. Barbosa,A. Ferreira,C. Teles,D. Pereira,R. Barros,E. Benavente,S. Ekins,R. Guido

ACS Infection Diseases. 2026-05-25

Scientific publications

Design and anti-rhinovirus activity of novel derivatives based on the pleconaril core

Полусинтетический алкалоид виндебурнол: синтез и его влияние на центральную нервную систему

Photoelectrocatalytic oxidation of levofloxacin on titanium dioxide nanotubes in a 0.9% NaCl solution

Ultrasound model of depression in rodents: a comprehensive analysis of validity, pathogenic mechanisms, and potential for translation to humans

Effective Influenza Treatment: A Comprehensive Review of Challenges and Advances

The efficacy, structure-activity relationship, and mode of action studies of a new generation of acridine/acridone-based antimalarials

Cytometric proteome profiling of GFP-tagged yeast for characterizing novel antifungals

Vindeburnol induces neuroprotection in rat traumatic brain injury via adrenergic receptor antagonism

Enhanced Antiviral Activity of Novel Umifenovir Derivatives Against SARS-CoV-2: Insights from an International Collaborative Study

Structural basis for EtfD-mediated coupling of β-oxidation and the respiratory chain in mycobacteria

Biodeterioration Aspects of the 16th Century Icon “Deesis Tier of Thirteen Figures” by the Fungus Iodophanus sp. STG-150: a Range of Materials for Biodegradation and Selection of Target Antiseptics

Photoelectrocatalytic degradation of molecular forms of non-steroidal anti-inflammatory drugs on TiO2 nanotubes in a 0.9% NaCl solution.

Comprehensive preclinical study of the procognitive effects, safety, and pharmacokinetics of vindeburnol

Impact on the virulence of Mycobacterium tuberculosis and non-tuberculous mycobacteria: focus on the development of anti-infective drugs

Исследование противотуберкулезного препарата макозинона (PBTZ169) на кишечную микробиоту и иммунитет у инбредных мышей

Protein kinase inhibitors: synthesis and molecular repurposing in three-dimensional cancer models

The formation of a ternary complex involving viral capsid protein 1 and two capsid-binding inhibitors explains the synergistic interactions observed in studies of combinations against rhinoviruses

Cryo-EM structure of HIV-1 reverse transcriptase with N-phenyl-1-(phenylsulfonyl)-1H-1,2,4-triazol-3-amine: a novel non-nucleoside HIV-1 inhibitor

The Mycobacterium tuberculosis sulfatase/dioxygenase Rv3406 is capable of inactivating the compound RCB18350.

Efficacy of the dispirotripiperazine PDSTP in SARS-CoV-2 infection models in Syrian golden hamsters

New heteroleptic palladium complexes with amino acid and bornane ligands: synthesis and antibacterial activity

Umifenovir (Arbidol) and acute rotavirus gastroenteritis: antiviral activity, mechanism of action, and a review and meta-analysis of clinical studies.

Исследования in vivo и in vitro, измерение противовирусной эффективности двойных комбинаций против инфекции вирусом Коксаки Б.

Discovery of Dual Targeting GSK-3β/HIV-1 Reverse Transcriptase Inhibitors as Neuroprotective Antiviral Agents

Real-time evaluation of macozinone activity against Mycobacterium tuberculosis through bacterial nanomotion analysis

Nitric oxide induces the distinct invisibility phenotype of Mycobacterium tuberculosis

Vindeburnol: A natural product-inspired chemical tool for central nervous system drug design

Dynamic features of virus protein 1 and substitutions in the 3-phenyl ring determine broad-spectrum activity of capsid-binding pyrazolopyrimidines

Indole-core inhibitors of influenza A neuraminidase: iterative medicinal chemistry and molecular modeling

The novel drug candidate VOMG kills Mycobacterium abscessus and other pathogens by inhibiting cell division

Modulating mycobacterial envelope Integrity for antibiotic synergy with benzothiazoles

Efficacy of macozinone in mice with genetically diverse susceptibility to tuberculosis infection

Characterization of the dispirotripiperazine derivative PDSTP as antibiotic adjuvant and antivirulence compound against Pseudomonas aeruginosa

Determination of alkaloid-inspired molecule vindeburnol in rabbit plasma by UPLC–HRMS and its application to pharmacokinetic studies and preliminary metabolite identification

Machine learning-aided search for ligands of P2Y6 and other P2Y receptors

Benzothiozinone derivatives with anti-tubercular activity−further side chain investigation

Molecular mechanism of rhinovirus escape from the pyrazolo[3,4-d]pyrimidine capsid-binding inhibitor OBR-5-340 via mutations distant from the binding pocket: derivatives that brake resistance

Antidepressant-like effect of the eburnamine-type molecule vindeburnol in rat and mouse models of ultrasound-induced depression

1‑Sulfonyl-3-amino‑1H‑1,2,4-triazoles as yellow fever virus inhibitors: synthesis and structure-activity relationship

Synthesis and evaluation of 9-aminoacridines with SARS-CoV-2 antiviral activity

Antiviral evaluation of dispirotripiperazines against hepatitis B virus

Side chain-modified benzothiazinone derivatives with anti-mycobacterial activity

CanB, a druggable cellular target in Mycobacterium tuberculosis

Pyrrolo[2,3-e]indazole as a novel chemotype for both influenza A virus and pneumococcal neuraminidase inhibitors

N-Phenyl-1-(phenylsulfonyl)-1H-1,2,4-triazol-3-amine as a new class of HIV-1 non-nucleoside reverse transcriptase inhibitor

Optimized LC-MS/MS quantification of tuberculosis drug candidate macozinone (PBTZ169), its dearomatized Meisenheimer Complex and other metabolites, in human plasma and urine

Antituberculosis macozinone extended-release tablets to enhance bioavailability: a pilot pharmacokinetic study in Beagle dogs

Mycobacterium tuberculosis dormancy: how to fight a hidden danger

A new benzothiazolthiazolidine derivative, 11726172, is active in vitro, in vivo, and against nonreplicat﻿ing cells of Mycobacterium tuberculosis

Bactericidal and anti-biofilm activity of the FtsZ inhibitor C109 against Acinetobacter baumannii

New drugs and novel cellular targets against tuberculosis

Multiple approaches to repurposing drugs for neuroblastoma

Broad-spectrum antiviral diazadispiroalkane core molecules block attachment and cell-to-cell spread of herpesviruses

PDSTP is the first drug in class to treat coronavirus infection

Dimethyl fumarate eliminates differentially culturable Mycobacterium tuberculosis in an intranasal murine model of tuberculosis

Thieno[2,3-d]pyrimidine-core compounds show activity against clinically relevant gram-positive bacteria

A proof-of-concept study for the efficacy of dispirotripiperazine PDSTP in a rabbit model of herpes simplex epithelial keratitis

Pyronaridine protects against SARS-CoV-2 infection in mouse

Copper(II) complexes with terpene derivatives of ethylenediamine: synthesis, and antibacterial, antifungal and antioxidant activity

Mycobacterium abscessus drug discovery using machine learning

Machine learning models for Mycobacterium tuberculosis in vitro activity: prediction and target visualization`

Targeting non-replicating Mycobacterium tuberculosis and latent infection: alternatives and perspectives (mini-review)

Development of machine learning models and the discovery of a new antiviral compound against yellow fever virus

Antistaphylococcal activity of the FtsZ inhibitor C109

Discovery of 5-Nitro-6-thiocyanatopyrimidines as Inhibitors of Cryptococcus neoformans and Cryptococcus gattii

Diazadispiroalkane derivatives are new viral entry inhibitors

Small molecules — prospective novel HCMV inhibitors

Pipeline of anti-Mycobacterium abscessus small molecules: Repurposable drugs and promising novel chemical entities

Nitric oxide-releasing compounds for the treatment of lung infections

Dispirotripiperazine-core compounds, their biological activity with a focus on broad antiviral property, and perspectives in drug design (mini-review)

Design and synthesis of pyrano[3,2-b]indolones showing antimycobacterial activity

6,11-Dioxobenzo[f]pyrido[1,2-a]indoles kill Mycobacterium tuberculosis by targeting iron-sulfur protein Rv0338c (IspQ), a putative redox sensor

WIN compounds: on the way to efficient antipicornaviral agent. A historical survey

Molecule property analyses of active compounds for Mycobacterium tuberculosis

Chemical, metabolic, and cellular characterization of a FtsZ inhibitor effective against Burkholderia cenocepacia

Development of macozinone for TB treatment: an update

The evolution of pleconaril: modified O-alkyl linker analogs have biological activity towards Coxsackievirus B3 Nancy

The cell division protein FtsZ as a cellular target to hit cystic fibrosis pathogens

Rv0579 is involved in the resistance to the TP053 antitubercular prodrug

A new benzothiazolthiazolidine derivative, 11726172, is active in vitro, in vivo, and against nonreplicating cells of Mycobacterium tuberculosis