Research Center of Biotechnology RAS
Medicinal Chemistry Laboratory
A full-cycle research group: molecular design, organic synthesis, biological testing, and publication data analysis.
Directions
Research program
The work is organized around therapeutic questions where a chemical hypothesis is quickly tested through experiments and publication data.
Tuberculosis
HIV
Influenza
Rhinovirus
Antibiotics
Drug resistance
Cancer
Dementia
Tuberculosis
HIV
Influenza
Rhinovirus
Antibiotics
Drug resistance
Cancer
Dementia
archive
Latest publications
Viruses
Русский Proof-of-Concept Study for the Efficacy of Dispirotripiperazine PDSTP in a Mouse Model of Herpes Simplex Herpetic Encephalitis
K. Pomeshikova,O. Riabova,N. Monakhova,I. Leneva,G. Sanna,V. Makarov
2026-08-28
European Journal of Medicinal Chemistry
Design and anti-rhinovirus activity of novel derivatives based on the pleconaril core
A. Egorova,O. Riabova,E. Kazakova,S. de Jonghe,D. Jochmans,J. Neyts,M. Schmidtke,M. Cogoni,V. Palmas,M. Khrenova,G. Sanna,V. Makarov
2026-08-26
Studies in Natural Products Chemistry
Полусинтетический алкалоид виндебурнол: синтез и его влияние на центральную нервную систему
L. Borets,Y. Zorkina,O. Abramova,V. Ushakova,E. Zubkov,V. Makarov
2026-08-19
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Laboratory news
2026-09-24
During the evening program on Moscow FM radio, Vadim Makarov—Head of the Laboratory of Biomedical Chemistry at the Federal Research Center of Biotechnology of the Russian Academy of Sciences—discussed the importance of preventing seasonal illnesses and answered questions about vaccination and the spread of infections. Full episode of the "Evening Roll Call" (Vechernyaya Poverka) program on Moscow FM radio:
2026-09-21
Laboratory Head Vadim Makarov participated in the 7th International Forum "Virology Days 2026" in St. Petersburg as a moderator and delivered a presentation titled "Development of broad-spectrum host-targeted antiviral drugs, using the drug candidate PDSTP as an example."
2026-09-01